![]() In anesthesiology, the importance of systematic reviews and meta-analyses has been highlighted, and they provide diagnostic and therapeutic value to various areas, including not only perioperative management but also intensive care and outpatient anesthesia. In 2009, the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement was published, and it greatly helped standardize and improve the quality of systematic reviews and meta-analyses. Following the Quality of Reporting of Meta-analyses (QUORUM) statement, and the appearance of registers such as Cochrane Library’s Methodology Register, a large number of systematic literature reviews have been registered. Since 1999, various papers have presented guidelines for reporting meta-analyses of RCTs. Usually, in order to obtain more reliable results, a meta-analysis is mainly conducted on randomized controlled trials (RCTs), which have a high level of evidence ( Fig. A meta-analysis is a valid, objective, and scientific method of analyzing and combining different results. During the systematic review process, the quality of studies is evaluated, and a statistical meta-analysis of the study results is conducted on the basis of their quality. Some of the content in this section is from Systematic reviews and meta-analyses: step by step guide created by Kate McAllister.A systematic review collects all possible studies related to a given topic and design, and reviews and analyzes their results. In that case, an integrative review is an appropriate strategy. Not all topics, however, have sufficient research evidence to allow a meta-analysis to be conducted. It is a systematic review that uses quantitative methods to synthesize and summarize the results.Īn advantage of a meta-analysis is the ability to be completely objective in evaluating research findings. Ī meta-analysis goes beyond critique and integration and conducts secondary statistical analysis on the outcomes of similar studies. More information on meta-analyses can be found in Cochrane Handbook, Chapter 9. Meta-analysis is the use of statistical methods to summarize the results of independent studies. By combining information from all relevant studies, meta-analysis can provide more precise estimates of the effects of health care than those derived from the individual studies included within a review. Not all systematic reviews contain meta-analysis. systematic presentation, and synthesis, of the characteristics and findings of the included studies.assessment of the validity of the findings of the included studies (e.g.a systematic search that attempts to identify all studies.clearly stated objectives with pre-defined eligibility criteria for studies. ![]() They are a significant piece of work (the Centre for Reviews and Dissemination at York estimates that a team will take 9-24 months), and to be useful to other researchers and practitioners they should have: Systematic reviews, just like other research articles, can be of varying quality. A systematic review answers a defined research question by collecting and summarizing all empirical evidence that fits pre-specified eligibility criteria.Ī meta-analysis is the use of statistical methods to summarize the results of these studies.
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